{"title":"Centellian24","description":"\u003cp\u003eCentellian24 is a Korean derma skincare brand from Dongkook Pharmaceutical, built around Centella asiatica and its purified actives such as madecassoside. The brand is best known by its Madeca line.\u003c\/p\u003e\n\u003cp\u003eIts hero product is the Madeca Cream, a soothing barrier moisturiser, supported by toners, ampoules and sun care that share the same Centella focus.\u003c\/p\u003e\n\u003cp\u003eThe calming Centella formulas suit \u003ca href=\"\/collections\/sensitive-skin\"\u003esensitive skin\u003c\/a\u003e and \u003ca href=\"\/collections\/redness-irritation\"\u003eredness and irritation\u003c\/a\u003e, with a focus on barrier recovery.\u003c\/p\u003e","products":[{"product_id":"centellian24-madeca-cream-time-reverse","title":"Centellian24 Madeca Cream Time Reverse","description":"\u003cp\u003e\u003cstrong\u003eSkin-Nomad's Take — At a Glance\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eActive-TECA, the brand's pharmaceutical-grade \u003ca class=\"sn-ilink\" href=\"\/collections\/centella-asiatica\"\u003eCentella\u003c\/a\u003e extract, with \u003ca class=\"sn-ilink\" href=\"\/collections\/retinol\"\u003eretinol\u003c\/a\u003e behind it\u003c\/li\u003e\n\u003cli\u003eElasticity up 23.5% over four weeks on Centellian24's own testing*\u003c\/li\u003e\n\u003cli\u003eRichly scented with essential oils, and an evening cream rather than a gentle one\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFirmness and a light finish are the two things people want from a moisturiser and rarely get in the same jar. The Centellian24 Madeca Cream Time Reverse works on the first through Active-TECA, the standardised Centella extract the brand describes as pharmaceutical grade, with retinol, adenosine and collagen amino acids behind it. Centellian24 came out of Dongkook Pharmaceutical's dermatology unit in South Korea, which is why the claims arrive with figures attached.\u003c\/p\u003e\n\u003ch3\u003eKey Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive-TECA is Centella broken out into its working compounds:\u003c\/strong\u003e Madecassic acid, asiaticoside and asiatic acid appear individually on the ingredient list rather than as a plant extract, which is the difference between a standardised material and a botanical note. TECA is the form used where collagen synthesis rather than simple soothing is the point, and madecassoside further down handles the calming half separately.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe measured change is elasticity, and it takes four weeks:\u003c\/strong\u003e Centellian24 record elasticity up 23.5% at four weeks, and moisture and elasticity holding for up to 240 hours.* They also publish an absorption figure of 251% faster, which is the kind of number that describes how a cream feels rather than what it does.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThere is retinol in here, and it is doing real work:\u003c\/strong\u003e It sits alongside adenosine, and the two prompt the skin's collagen-producing cells by separate routes. It is well down the list rather than at a treatment-serum dose, but it is present, and it is the reason this reads as an evening cream rather than a barrier cream that happens to firm.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCeramide NP, ectoin and glycogen hold the barrier while that happens:\u003c\/strong\u003e Ceramide NP replaces a barrier lipid directly, ectoin is the stress-protectant that keeps water bound in dry air, and phytosphingosine sits with them. Collagen amino acids and hydrolysed elastin are protein fragments rather than structural collagen, so read them as support for the surface rather than as rebuilding anything underneath it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eTexture \u0026amp; Finish\u003c\/h3\u003e\n\u003cp\u003eIt has the substance of a firming cream without the weight, sinking in rather than sitting on the surface. The scent is the thing you notice first: this is perfumed with real essential oils rather than a light fragrance, and it is closer to an aromatherapy cream than to a clinical one.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e Two things to know before buying. It contains retinol, so build up to it gradually in the evening rather than using it nightly from the start, and we don't recommend retinoids during pregnancy or while breastfeeding. It also carries a long list of essential oils, including lavender, bergamot, rose, jasmine, geranium and citrus peel oils, with limonene, linalool, citral and camphor declared as allergens. Skin that reacts to aromatic plants should treat this as one to patch test rather than one to trust on the strength of the Centella.\u003c\/p\u003e\n\u003ch3\u003eIdeal For\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin types:\u003c\/strong\u003e Normal, dry and mature skin, plus combination skin that needs real hydration in the dry zones. Not the right cream for fragrance-sensitive or reactive skin, whatever the Centella content suggests.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin concerns:\u003c\/strong\u003e Loss of elasticity and firmness, dryness, dullness and uneven texture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBest used by:\u003c\/strong\u003e Skin in its thirties and beyond that wants firmness and lasting hydration from one step, and someone who actively enjoys a scented cream rather than tolerating one.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eFAQ\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How does this compare to a dedicated firming serum?\u003c\/strong\u003e\u003cbr\u003eA: A firming serum concentrates on one pathway and leaves the moisturising to whatever goes over it. The Centellian24 Madeca Cream Time Reverse carries Active-TECA, retinol and adenosine for firmness, ceramide NP and ectoin for the barrier, and two forms of hyaluronic acid for hydration, so it is a complete moisturiser rather than a step that needs another one behind it.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Is Centella only a calming ingredient?\u003c\/strong\u003e\u003cbr\u003eA: Calming is its reputation, but it is not the whole record. Centella Asiatica has a long history in wound repair, and TECA is the standardised extract used where collagen synthesis is the point rather than soothing alone. In this cream TECA is doing structural work alongside the retinol, while madecassoside handles the calming half separately.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Can I use this alongside Vitamin C, acids or another retinoid?\u003c\/strong\u003e\u003cbr\u003eA: Vitamin C in the morning and this in the evening is a clean split. Acids and other retinoids are the ones to be careful with, because this cream already contains retinol, so stacking it with a retinoid serum or an exfoliating acid on the same night is how people end up sore. Keep those on alternate evenings. It goes on after your serum, with sunscreen as the final step in the morning.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Can I use this cream during pregnancy?\u003c\/strong\u003e\u003cbr\u003eA: We recommend pausing it, for two reasons that are both on Centellian24's own ingredient list. It contains retinol, and our \u003ca href=\"\/pages\/pregnancy-safe-skincare\"\u003epregnancy safe skincare guide\u003c\/a\u003e excludes every topical retinoid during pregnancy. It also contains rosemary leaf oil, which the guide excludes unless the brand states a type that is not camphor-rich, and Centellian24 does not. For firmness while pregnant, the guide points to peptides, hyaluronic acid, niacinamide and bakuchiol instead, and our \u003ca href=\"\/collections\/pregnancy-safe\"\u003epregnancy safe collection\u003c\/a\u003e has creams built on them. This is not medical advice, so if you have a specific concern, check with your midwife or GP.\u003c\/p\u003e\n\u003cp\u003eMost of a firming cream's persuasion happens in the mirror ten minutes after you apply it; this one asks to be judged four weeks later instead.\u003c\/p\u003e\n\u003cp class=\"sn-claims\"\u003e\u003csmall\u003e* Figures published by Centellian24 for the Madeca Cream Time Reverse: skin elasticity improvement 23.5% after four weeks; moisture and elasticity sustained for up to 240 hours; absorption 251% faster. The brand describes the product as clinically tested across the face and neck but does not publish the panel size, the testing body or the measurement method. Brand-commissioned testing rather than an independent trial; results vary between individuals.\u003c\/small\u003e\u003c\/p\u003e\n\u003cp class=\"sn-explore-more\"\u003e\u003cstrong\u003eExplore more\u003c\/strong\u003e\u003cbr\u003eExplore the \u003ca href=\"\/collections\/centella-asiatica\"\u003eCentella Asiatica\u003c\/a\u003e collection, target \u003ca href=\"\/collections\/wrinkles-aging\"\u003ewrinkles \u0026amp; fine lines\u003c\/a\u003e, or see more from \u003ca href=\"\/collections\/centellian24\"\u003eCentellian24\u003c\/a\u003e.\u003c\/p\u003e","brand":"Centellian24","offers":[{"title":"Default Title","offer_id":59229188587854,"sku":"CTS09-MC","price":13.85,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0798\/5057\/0062\/files\/CTS09-MC.png?v=1778671450"},{"product_id":"centellian24-expert-madeca-cream-active-renew-pdrn","title":"Centellian24 Expert Madeca Cream Active Renew PDRN","description":"\u003cp\u003e\u003cstrong\u003eSkin-Nomad's Take — At a Glance\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eTECA-PDRN complex at 20,000 ppm, with pure PDRN at 2,000 ppm\u003c\/li\u003e\n\u003cli\u003eMadecassic acid at 1,600 ppm and nine forms of \u003ca class=\"sn-ilink\" href=\"\/collections\/hyaluronic-acid\"\u003ehyaluronic acid\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eA rich, scented night cream for mature and barrier-worn skin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSkin that has turned tight, quick to redden and slower to bounce back is telling you about its barrier before anything else. Centellian24 Expert Madeca Cream Active Renew PDRN answers that with what the brand calls its TECA-PDRN complex at 20,000 ppm: madecassic acid at 1,600 ppm, the isolated \u003ca class=\"sn-ilink\" href=\"\/collections\/centella-asiatica\"\u003eCentella\u003c\/a\u003e compound their research is founded on, and pure PDRN at 2,000 ppm for the repair side that calming alone does not reach. Centellian24 came out of Dongkook Pharmaceutical's dermatology unit, which is why the Centella arrives as a named compound at a stated dose rather than as a plant on the label.\u003c\/p\u003e\n\u003ch3\u003eKey Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMadecassic acid at 1,600 ppm does the structural work:\u003c\/strong\u003e Together with asiaticoside and asiatic acid, both named separately on the list, it strengthens barrier function and calms the reactivity that comes with a barrier under strain. Tightness and sensitivity drop away with continued use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe PDRN here is drawn from five sources, not one:\u003c\/strong\u003e Centellian24 describe it as 5D-PDRN, taken from Centella, salmon, rose, marine sources and houttuynia, and declare the pure fraction at 2,000 ppm as Sodium DNA. PDRN acts on adenosine A2A receptors at the skin surface, the pathway through which the skin's own repair signalling is switched on, and that activity is what built its name across years of clinical and injectable work. Bringing it into a daily cream is the newer step and the topical research is still growing, which is exactly why a stated dose at this level is worth reading. It is not vegan, because salmon is one of the five.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNine forms of hyaluronic acid is not a marketing count:\u003c\/strong\u003e Sodium hyaluronate, hyaluronic acid itself, a crosspolymer, two hydrolysed forms, potassium hyaluronate and three silanol and cationic variants each behave differently on the skin, binding water at different depths and clinging to it for different lengths of time. Niacinamide reinforces the skin's own lipid production underneath them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlushing and visible redness get actives of their own:\u003c\/strong\u003e Caffeine constricts the small vessels near the surface, glutathione and ascorbic acid work the oxidative side of tone, and Rosa Damascena flower water sits high on the list calming the skin they act on. Colour settles rather than being buried under moisture.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eTexture \u0026amp; Finish\u003c\/h3\u003e\n\u003cp\u003eIt is a proper cream in weight, closer to a night cream than to a daily gel, and it settles to a soft, sealed finish rather than a matte one. On dry and mature skin that weight is the point, because holding water in place is half of what a barrier cream exists to do.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e This is a scented cream. Lavender, bergamot, orange peel, rosemary and chamomile oils sit in the formula with limonene and linalool declared as allergens, so skin that reacts to aromatic plants should patch test rather than rely on the Centella content. Combination skin with dry patches will also find this better suited to evenings than to a summer morning.\u003c\/p\u003e\n\u003ch3\u003eIdeal For\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin types:\u003c\/strong\u003e Mature, dry and barrier-worn skin, plus combination skin with dry patches. Fragrance-sensitive skin should look elsewhere in the range.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin concerns:\u003c\/strong\u003e Loss of firmness and elasticity, fine lines, persistent dryness, tightness and redness.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBest used by:\u003c\/strong\u003e Someone in their forties or beyond whose skin has stopped tolerating the actives it used to will find this a way back to comfort without giving up on results.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eFAQ\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How is this different from a lightweight Centella serum?\u003c\/strong\u003e\u003cbr\u003eA: A Centella serum delivers the calming compounds and very little else, which is the right choice on skin that is only irritated. This pairs madecassic acid at 1,600 ppm with nine hyaluronic acids and a rich base, so the same soothing arrives with the water and the seal that barrier-worn skin also needs. If serums have calmed your skin without stopping it feeling tight, the richer format is the part that has been missing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Does PDRN in a cream do what an injectable PDRN treatment does?\u003c\/strong\u003e\u003cbr\u003eA: No, and it is worth being clear about that. An injection places the molecule beneath the skin surface, whereas a cream works from the outside in, and results from one format do not transfer to the other. Applied to the surface it works on the same repair signalling from the outside, on a timescale of weeks rather than days, which is a different rhythm from the comfort the Centella and the hyaluronic acids deliver on day one.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Where does a cream this rich go in a routine?\u003c\/strong\u003e\u003cbr\u003eA: It is the last skincare step in the evening, after cleansing, any toner or essence, and your treatment step. In the morning it goes under sunscreen, which stays the final skincare step of all. It is a complete moisturising layer on its own, so nothing needs to go over it at night.\u003c\/p\u003e\n\u003cp\u003ePrinting the ppm figures on the front is a small thing, and it tells you Centellian24 expect the people buying this cream to check them.\u003c\/p\u003e\n\u003cp class=\"sn-explore-more\"\u003e\u003cstrong\u003eExplore more\u003c\/strong\u003e\u003cbr\u003eExplore the \u003ca href=\"\/collections\/centella-asiatica\"\u003eCentella Asiatica\u003c\/a\u003e collection, target \u003ca href=\"\/collections\/wrinkles-aging\"\u003ewrinkles \u0026amp; fine lines\u003c\/a\u003e, or see more from \u003ca href=\"\/collections\/centellian24\"\u003eCentellian24\u003c\/a\u003e.\u003c\/p\u003e","brand":"Centellian24","offers":[{"title":"Default Title","offer_id":59872798703950,"sku":"CTS12-C","price":14.95,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0798\/5057\/0062\/files\/CTS12-C.png?v=1781890652"},{"product_id":"centellian24-360-shot-pdrn-lifting-eye-cream","title":"Centellian24 360º Shot PDRN lifting Eye cream","description":"\u003cp\u003e\u003cstrong\u003eSkin-Nomad's Take — At a Glance\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFour retinoid forms with adenosine on collagen, in a light eye cream\u003c\/li\u003e\n\u003cli\u003eA five-ceramide barrier underneath, so thin skin can take them\u003c\/li\u003e\n\u003cli\u003eCentellian24's TECA and PDRN complex; fragranced\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe skin around your eyes gives up firmness before the rest of your face does, and by the time you notice it a hydrating eye cream is no longer the answer. The Centellian24 360º Shot PDRN lifting Eye cream comes at that with four retinoid forms and adenosine working on collagen, a five-ceramide barrier holding the area steady underneath, and the TECA and PDRN complex the range is named for. Centellian24 formulate in South Korea out of Dongkook Pharmaceutical's dermatology unit, which is how a compound better known from clinics ended up in a light eye cream.\u003c\/p\u003e\n\u003ch3\u003eKey Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFour retinoid forms reach the same receptor at different speeds:\u003c\/strong\u003e Retinol converts to its active form in two steps, retinal in one, hydroxypinacolone retinoate binds the receptor directly without converting at all, and retinyl palmitate is the slowest of the four, an ester that has to become retinol first. The collagen signal arrives staggered rather than all at once, with adenosine prompting the same cells alongside them, and slackness at the outer corner is the slow, cumulative change they are working on.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe ceramide complex earns its place by making that survivable:\u003c\/strong\u003e Ceramides NP, AP, AS, NS and EOP reinforce the skin's lipid barrier, with cholesterol and phytosterols alongside them, beta-glucan holding water below the surface, and Centella and Portulaca Oleracea settling the irritation retinoid use brings. On skin this thin, that is the difference between a retinoid working and a retinoid flaking.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBrightening arrives from three directions at once:\u003c\/strong\u003e Ascorbic acid works on the pigment that discolours the under-eye, glutathione takes the oxidative side of the same problem, and coffee seed extract brings caffeine to the fluid and dilated vessels behind the puffy, shadowed look. Those are separate causes of a tired-looking eye, and this covers all three.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePDRN is here as part of the brand's complex rather than as a solo act:\u003c\/strong\u003e Sodium DNA sits in the upper half of the list alongside the TECA compounds. Centellian24 do not publish its source on this product, so we will not name one; what is worth knowing is that PDRN came to skincare with a reputation built in injectable and wound-healing use, and the topical research behind it is younger and still growing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eTexture \u0026amp; Finish\u003c\/h3\u003e\n\u003cp\u003eLight for the length of its ingredient list, closer to a cream-gel than to a balm. It layers cleanly at the eye step, under a night cream or a facial oil later in the evening.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e Four retinoid forms is a lot for the thinnest skin on your face, so this is an evening cream to build up to gradually rather than one to use at full frequency from the start. We don't recommend retinoids during pregnancy or while breastfeeding. It is also fragranced, with bergamot and lemon peel oils and citronellol, linalool and limonene declared, which is worth knowing this close to the eye.\u003c\/p\u003e\n\u003ch3\u003eIdeal For\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin types:\u003c\/strong\u003e Combination, normal, dry and mature skin, including an eye area that has turned dry. Not the right choice for skin that reacts to fragrance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin concerns:\u003c\/strong\u003e Fine lines and crow's feet, loss of firmness, dehydration, dullness and a tired look, and uneven tone around the eye.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBest used by:\u003c\/strong\u003e People in their forties and beyond who would rather run one loaded eye cream than three thin ones will get the most from this, because the ceramide base is what lets that many actives share a single step.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eFAQ\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How does this compare to a standard eye cream?\u003c\/strong\u003e\u003cbr\u003eA: A standard eye cream is a hydrating base with one or two actives in it. This carries four retinoid forms, five ceramides, ascorbic acid, glutathione, adenosine, Centella and PDRN in a single light texture, which is a full-face serum's worth of actives applied at the eye step.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Are retinol, retinal and hydroxypinacolone retinoate three names for the same thing?\u003c\/strong\u003e\u003cbr\u003eA: No. They are separate molecules that end up acting on the same receptor by different paths: retinol needs two conversion steps inside the skin, retinal needs one, and hydroxypinacolone retinoate binds the receptor directly with no conversion. Retinyl palmitate, also in the formula, is slower still. Using them together spreads the retinoid effect across different speeds instead of concentrating it in one fast-acting form.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Can I use this if I already use a retinoid on the rest of my face?\u003c\/strong\u003e\u003cbr\u003eA: Yes, and it works perfectly well as the whole eye step on its own. It goes on in the evening at the eye stage, after your serum and before your moisturiser, and the ceramide and Centella content is there precisely so the eye area does not dry out while everything else is being pushed. It also sits naturally alongside a morning brightening serum, since pigment work and collagen work run on opposite halves of the day.\u003c\/p\u003e\n\u003cp\u003eThe eye step is normally where a routine eases off, and this is a cream that goes the other way.\u003c\/p\u003e\n\u003cp class=\"sn-explore-more\"\u003e\u003cstrong\u003eExplore more\u003c\/strong\u003e\u003cbr\u003eTarget \u003ca href=\"\/collections\/dark-circle\"\u003edark circles\u003c\/a\u003e, work on \u003ca href=\"\/collections\/wrinkles-aging\"\u003ewrinkles \u0026amp; fine lines\u003c\/a\u003e, or see more from \u003ca href=\"\/collections\/centellian24\"\u003eCentellian24\u003c\/a\u003e.\u003c\/p\u003e","brand":"Centellian24","offers":[{"title":"Default Title","offer_id":59873157480782,"sku":"CTS12-I","price":16.9,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0798\/5057\/0062\/files\/CTS12-I.png?v=1781890563"}],"url":"https:\/\/skin-nomad.fr\/collections\/centellian24.oembed","provider":"Skin-Nomad","version":"1.0","type":"link"}